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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Br J Haematol. 2019 Dec 30;188(6):985–993. doi: 10.1111/bjh.16251

Figure 3. 5HMF significantly reduces the effect of 0% oxygen on SCT blood flow velocity.

Figure 3

The steady state flow velocity was measured for 6 SCT blood samples at 21% oxygen and then at 0% oxygen. (Because oxygen tension is controlled by diffusion, it is possible that there is a small nonzero oxygen concentration from ambient diffusion even when 0% oxygen is flowing into the system.) The percent reduction in flow velocity at 0% varied from 7% to 60% (black dots). After treatment with lmM 5HMF, the maximum velocity reduction at 0% oxygen was about 11% (grey dots). Responses represent the percent change in mean, steady state velocity after a drop from atmospheric to 0% oxygen concentration in the device. Differences are significant based on a Kruskal-Wallis one-way analysis of variance. Error bars represent one standard deviation of the propagated uncertainty.