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(A) Dentate Gyrus mushroom spine density lowers by about one third in irradiated animals. (C) The Apical CA2 underwent reduced mushroom spine density in both dosages. (B,D) The basal CA2 overall, and mushroom spine density at only 0.25 Gy. (E,F) Apical and basal CA1 mushroom spines decrease in a dose-dependent manner in irradiated animals. Average ± SEM (n = 5); *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.
