Table 1:
Patient Demographics and Clinical Ratings of Parkinsonian Motor Signs
| Patient ID | UD1015 | UD1018 | UD1019 | |
|---|---|---|---|---|
| Age/Sex | 63 / F | 60 / F | 52 / M | |
| Time from diagnosis to recording (yrs) | 7 | 10 | 6 | |
| Handedness | Right | Right | Right | |
| DBS side | Left | Right | Right | |
| Side of disease onset | Right | Left | Left | |
| Pre-operative prominent features | Dyskinesias, fluctuations, rigidity, tremor, bradykinesia | Rigidity, bradykinesia, gait imbalance | Dyskinesias, fluctuations, freezing, bradykinesia, rigidity, gait disturbance | |
| Days from surgery to externalized recordings | 4 | 7 | 5 | |
| Total possible | UPDRS-III | |||
| 12 / 4 | Tremor (UE / LE)a | 2 / 3 | 1 / 0 | 2 / 0 |
| 4 / 4 | Rigidity (UE / LE)a | 2 / 2 | 2 / 3 | 2 / 2 |
| 12 / 8 | Bradykinesia (UE / LE)a | 6 / 4 | 8 / 7 | 4 / 1 |
| 32 | Axialc | 9 | 14 | 22 |
| 44 (132) | Total Unilateralb (Total Bodyc) | 19 (53) | 21 (44) | 11 (46) |
a
Tremor, rigidity and bradykinesia sub-scores are reported in accordance with those defined by Goetz et al. (2008) (Goetz et al., 2008) and reported here are unilateral scores (contralateral to the side from which LFPs were recorded) and collected in the off-medication state prior to DBS implantation.
b
Total Unilateral scores consist of adding Tremor, Rigidity and Bradykinesia (UE & LE) subscores.
c
Total scores and axial scores reported here include the entire( bilateral) UPDRS-III subscore, in order to give a sense of disease state.