Skip to main content
. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Neurobiol Dis. 2020 Feb 5;139:104786. doi: 10.1016/j.nbd.2020.104786

Figure 4: Iron chelation and mitophagy induction rescue sensitivity of catp-6 to rotenone exposure.

Figure 4:

Sensitivity of N2 and catp-6(ok3473) mutant worms to the mitochondrial toxin, rotenone, measured as percent survival ± SD in worms exposed to (A) the 2.5 mM iron chelator calcium-EDTA (Ca-EDTA) or (B) the 50 μM mitophagy-inducing agents (TFEB enhancer and urolithin A) throughout development (n=2, p-value calculated using ordinary two-way ANOVA and Tukey’s multiple comparisons test). All the p-values are represented as *p < 0.05, **p<0.01 and ***p<0.001, ****p<0.0001.