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. 2020 Feb 5;253(2):87–99. doi: 10.1007/s00232-020-00108-3

Fig. 5.

Fig. 5

Aggregation free energy profiles of WT vs. S66F, R126H, R126L (a), and WT vs. E299K, T310I, and R333W (b). The APR1 and 2 represent aggregation-prone regions 1 and 2 that comprise of ~ 50–150 and ~ 270–390 residues, respectively. AR represents aggregating region, which corresponds to 402–452 residues