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. 2020 Apr 11;7:13. doi: 10.1186/s40580-020-00223-w

Table 1.

Comparison of recent PfLDH detection studies

Diagnosis Target Bio-recognition Output LOD Volume References
Microfluidic microplate PfLDH in buffer Antibody Fluorescence intensity 0.025 pg/μL 5 μL This study
Microfluidic microplate PfLDH in human serum Antibody Fluorescence intensity 1 pg/μL 5 μL This study
ELISA PfLDH in buffer Antibody Absorbance 0.1 pg/μL 100 μL This study
Lateral flow immunoassay PfLDH in buffer Antibody Colorimetric assay 10 pg/μL 30 μL [31]
AuNPs based aptasensor PfLDH in lysed RBCsa solution (Mimic real sample) Aptamer Colorimetric assay 38 pg/μL 10 μL [32]
MNP-Qdot aptasensor PfLDH in buffer Aptamer Fluorescence intensity 0.0066 pg/μL 100 μL [33]
Aptamer-tethered enzyme capture (APTEC) assay PfLDH in buffer Aptamer Colorimetric assay 4.9 pg/μL 10 μL [34]
Aptamer-tethered enzyme capture (APTEC) assay PfLDH in serum Aptamer Colorimetric assay 50 pg/μL 40 μL [35]

aRBC red blood cells