Table 3.
Antibacterial activity of P. granatum leaf extracts by microdilution method: Minimal Inhibitory Concentration was expressed in mg/mL (diameters of inhibition zones were measured in millimeter scale).
| Extract | Staphylococcus aureus | Escherichia coli | ||||
|---|---|---|---|---|---|---|
| Standard strain ATCC 25923 | Penicillin-resistant strain | Methicillin-resistant strain | Standard strain ATCC 25922 | Penicillin-resistant strain | Multidrug-resistant strain | |
| Hexane extract | >5 (-) | >5 (-) | >5 (-) | >5 (-) | >5 (-) | >5 (-) |
| Chloroform extract | 5 (-) | >5 (-) | >5 (-) | 2.5 (-) | 2.5 (-) | 5 (-) |
| Ethyl acetate extract | 5 (-) | >5 (-) | 2.5 (8) | 2.5 (8) | >5 (-) | 5 (-) |
| Ethanol extract | 2.5 (17) | 2.5 (14) | 2.5 (8) | 2.5 (13) | 5 (13) | 5 (-) |
| Aqueous extract | 2.5 (19) | 5 (15) | 5 (10) | 1.25 (13) | 5 (14) | 5 (12) |
| TOF extract | 0.625 (14) | 2.5 (15) | 1.25 (17) | 0.625 (16) | 2.5 (12) | 5 (12) |
| Amoxicillin | 0.001 | 0.064 | 0.128 | 0.001 | 0.256 | 0.512 |
| Cefotaxime | 0.001 | 0.002 | 0.128 | 0.001 | 0.001 | 0.512 |