Figure 2.

Effect of nintedanib on (a) liver weight and concentration in liver tissue of (b) myeloperoxidase (optical density), (c) serum alanine aminotransferase, and (d) serum aspartate aminotransferase during the preventive phase. Data are presented as mean ± standard error of the mean; n = 5 per group. Statistical significance is shown as: ^∗p < 0.05, ^∗∗p < 0.01, ^∗∗∗p < 0.001, ^∗∗∗∗p < 0.0001. ALT: alanine aminotransferase; ASP: aspartate aminotransferase; CCL₄: carbon tetrachloride; ns: not significant.