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. 2020 Mar 31;2020:3867198. doi: 10.1155/2020/3867198

Figure 7.

Figure 7

Effect of nintedanib on (a) total liver collagen and concentration in liver tissue of (b) TIMP-1, (c) IL-1β, and (d) IL-6 during the therapeutic phase. Data are presented as mean ± standard error of the mean; n = 5 per group. Statistical significance is shown as p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001. CCL4: carbon tetrachloride; IL-1β: interleukin-1β; IL-6: interleukin-6; ns: not significant; TIMP-1: tissue inhibitor of metalloproteinase.