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Biphasic dissolution experiments in (A) Bi-FaSSIF-V2 medium (BiPHa+), (B) Model of Xu et al. [33], (C) Bi-FaSSIF-V1 medium (BiPHa+), (D) Buffer without surfactant (BiPHa+); API concentration in the 1-decanol layer (red line, mean value and standard deviation); dissolved ritonavir in the aqueous medium (black line, mean value and standard deviation); pH values (blue line). All experiments were done in triplicate (n = 3).
