Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Feb 28;12(3):151. doi: 10.3390/toxins12030151

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Concepts of circadian disruption, chronodisturbance and chronodisruption. As compared to a normal circadian rhythm, circadian disruptions are characterized by altered circadian rhythm that may be short or long lived. Chronodisturbance is a chronic disruption of circadian rhythms that somehow leads to adaptive phenomena that limit its negative impact. Chronodisruption is a chronic disruption of circadian rhythms that results in disease. Chronodisruptors (not shown) are the factors driving chronodisruption. The normal circadian rhythm is shown as a green line in the left panel and as a discontinuous line in the other panels. A red line represents the altered circadian rhythm in the three left panels. Please note the different timelines shown in the horizontal axis, with chronodisturbance and chronodisruption implying chronicity.