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. 2020 Mar 14;9(3):53. doi: 10.3390/biology9030053

Figure 7.

Figure 7

Time evolution of negative contrast (ΔSNR%; signal-to-noise ratio) produced by USPIO derivatives at the level of TPC-1 tumors (A). Evidence of the presence of injected USPIO derivatives by anti-polyethylene glycol (PEG) antibody immunostaining in TPC-1 tumors grafted into athymic nude mice (all sacrificed after 130 min post-injection) (B). Analysis of the staining of iron nanoparticles by the anti-PEG antibody on TPC-1 tumors (C). The results shown in the box and whisker plots are statistically analyzed using the Mann–Whitney test: ** = p < 0.01 vs. USPIO-NSP; §§ = p < 0.01 vs. non-injected mice.