Table 3.
Summary of Results for QbD—Niosomal Dispersions.
| Batch ID # | RESULTS (NIOSOMAL DISPERSION) | |||||
|---|---|---|---|---|---|---|
| Dispersion Formed or Not | Organoleptic Properties | Entrapment Efficiency (%) | Particle Size (nm) | Polydispersity Index | Zeta Potential (mV) | |
| DND-1 | No | N/A | N/A | N/A | N/A | N/A |
| DND-2 | Yes | White Milky | 81.48 ± 0.07 | 423.27 ± 16.48 | 0.294 ± 0.04 | −75.63 ± 0.61 |
| DND-3 | Yes | White Milky | 93.69 ± 0.05 | 374.80 ± 9.48 | 0.289 ± 0.01 | −63.83 ± 4.26 |
| DND-4 | Yes | White Milky | 75.30 ± 0.06 | 154.40 ± 1.47 | 0.144 ± 0.02 | −54.13 ± 1.16 |
| DND-5 | Yes | White Milky | 84.79 ± 0.06 | 161.87 ± 10.83 | 0.330 ± 0.03 | −52.10 ± 1.51 |
| DND-6 | Yes | White Milky | 89.38 ± 0.03 | 411.20 ± 22.53 | 0.235 ± 0.03 | −43.03 ± 0.59 |
| DND-7 | Yes | White Milky | 91.43 ± 0.01 | 655.07 ± 46.64 | 0.276 ± 0.02 | −46.30 ± 0.87 |
| DND-8 | Yes | White Milky | 83.06 ± 0.04 | 759.87 ± 16.66 | 0.316 ± 0.01 | −51.03 ± 0.15 |
| DND-9 | Yes | White Milky | 84.69 ± 0.03 | 377.13 ± 10.90 | 0.322 ± 0.02 | −69.53 ± 0.40 |
| DND-10 | Yes | White Milky | 80.48 ± 0.03 | 346.13 ± 6.03 | 0.303 ± 0.01 | −58.30 ± 0.66 |
| DND-11 | Yes | White Milky | 82.54 ± 0.05 | 874.77 ± 109.42 | 0.394 ± 0.01 | −57.53 ± 1.86 |
| DND-12 | Yes | White Milky | 70.38 ± 0.20 | 457.10 ± 12.21 | 0.328 ± 0.03 | −38.50 ± 2.14 |
| DND-13 | Yes | White Milky | 89.33 ± 0.11 | 709.60 ± 24.44 | 0.345 ± 0.01 | −81.67 ± 2.30 |
| DND-14 | Yes | White Milky | 84.64 ± 0.03 | 919.87 ± 64.56 | 0.371 ± 0.01 | −54.67 ± 1.20 |
| DND-15 | Yes | White Milky | 83.93 ± 1.42 | 794.73 ± 9.07 | 0.324 ± 0.01 | −57.60 ± 2.01 |
| DND-16 | Yes | White Milky | 82.71 ± 0.11 | 56237.83 ± N/A | N/A | 11.43 ± 0.76 |
| DND-17 | Yes | White Milky | 63.90 ± 0.12 | 616.33 ± 7.02 | 0.348 ± 0.01 | −41.53 ± 0.72 |
| DND-18 | Yes | White Milky | 80.75 ± 0.02 | 435.77 ± 27.99 | 0.441 ± 0.05 | −40.23 ± 1.30 |
| DND-19 | Yes | White Milky | 70.41 ± 0.05 | 460.95 ± 12.07 | 0.320 ± 0.02 | −60.07 ± 0.78 |
| DND-20 | Yes | White Milky | 95.58 ± 0.03 | 355.30 ± 8.11 | 0.282 ± 0.01 | −58.53 ± 1.33 |
| DND-21 | Yes | White Milky | 74.56 ± 0.06 | 823.77 ± 19.59 | 0.334 ± 0.01 | −53.77 ± 0.95 |
| DND-22 | Yes | White Milky | 77.68 ± 0.06 | 444.37 ± 0.11 | 0.318 ± 0.01 | −51.17 ± 0.81 |
| DND-23 | Yes | White Milky | 76.48 ± 0.10 | 439.70 ± 56.28 | 0.273 ± 0.03 | −47.23 ± 1.75 |
| DND-24 | Yes | White Milky | 80.41 ± 0.09 | 680.00 ± 15.57 | 0.292 ± 0.01 | −34.13 ± 1.17 |
| DND-25 | Yes | White Milky | 83.04 ± 0.06 | 505.13 ± 20.78 | 0.261 ± 0.03 | −48.73 ± 1.10 |
| DND-26 | Yes | White Milky | 82.36 ± 0.03 | 487.03 ± 30.69 | 0.304 ± 0.01 | −48.73 ± 0.81 |
| DND-27 | Yes | White Milky | 91.59 ± 0.84 | 479.60 ± 7.79 | 0.310 ± 0.02 | −49.53 ± 2.48 |
| DND-28 | Yes | White Milky | 86.12 ± 0.78 | 521.80 ± 23.80 | 0.310 ± 0.00 | −54.17 ± 1.25 |
| DND-29 | Yes | White Milky | 92.34 ± 0.68 | 480.70 ± 24.61 | 0.302 ± 0.03 | −58.60 ± 0.44 |