. 2020 Feb 27;12(3):203. doi: 10.3390/pharmaceutics12030203

Table 6.

Validation: precision and accuracy data for catechin hydrate (CH) in different biomatrixes. LOQQC, lower limit of quantification for quality control; LQC, lower QC; MQC, medium QC; HQC, high QC.

Biomatrix	Quality Controls Samples	Theoretical Concentration (ng mL⁻¹) or (ng g⁻¹)	Intra-Batch Precision			Inter-Batch Precision			Recovery (%)
Biomatrix	Quality Controls Samples	Theoretical Concentration (ng mL⁻¹) or (ng g⁻¹)	Observed Concentration (ng mL⁻¹) or (ng g⁻¹) ± S.D.	Accuracy (%)	Precision (%C.V.)	Observed Concentration (ng mL⁻¹) or (ng g⁻¹) ± S.D.	Accuracy (%)	Precision (%C.V.)	Recovery (%)
Brain Homogenate	LOQQC	1.01	0.99 ± 0.03	98.02	3.03	0.98 ± 0.04	97.03	2.90	81.47
	LQC	2.90	2.85 ± 0.09	98.28	3.16	2.84 ± 0.11	97.93	2.44	83.48
	MQC	410.00	407.61 ± 11.36	99.41	2.79	403.17 ± 12.54	98.33	1.42	80.17
	HQC	800.00	789.67 ± 18.64	98.47	3.81	784.69 ± 19.21	98.09	0.72	81.38
Lungs Homogenate	LOQQC	1.01	0.98 ± 0.04	97.03	4.08	0.97 ± 0.06	96.04	2.34	80.25
	LQC	2.90	2.83 ± 0.11	97.59	3.89	2.81 ± 0.16	96.90	1.04	81.67
	MQC	410.00	404.71 ± 13.02	98.71	3.22	402.37 ± 14.17	98.14	0.59	82.49
	HQC	800.00	779.25 ± 19.61	97.41	2.52	775.43 ± 20.18	96.93	0.39	81.52
Plasma	LOQQC	1.01	0.96 ± 0.03	95.05	3.13	0.94 ± 0.04	93.07	2.32	80.57
	LQC	2.90	2.86 ± 0.14	98.62	4.90	2.85 ± 0.15	98.28	1.94	82.61
	MQC	410.00	402.33 ± 11.42	98.13	2.84	401.34 ± 12.69	97.89	0.66	83.46
	HQC	800.00	778.67 ± 21.64	97.33	2.78	774.18 ± 22.37	96.77	0.39	84.51

Values (mean ± SD) are derived from six replicates.