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Evaluation of skin barrier function in each experimental group using oxazolone-induced atopic dermatitis model: (A) Transepidermal water loss (TEWL); (B) Stratum corneum hydration (SCH); and (C) skin thickness. Results are expressed as mean ± SD (n = 3). Significant statistical differences: * p < 0.05, ** p < 0.01 comparison with the basal state. + p < 0.05, ++ p < 0.01 comparison with Day 15 (first administration of PGZ-NE).
