Table 3.
Receptor binding sites and mutant sites analysis of the isolates.
| Virus | Subtypes | HA a | HAa | PB2 | NA b | M2 | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 155 | 159 | 183 | 190 | 225 | 226 | 227 | 228 | 271 | 591 | 627 | 701 | 119 | 292 | 274 | 26 | 27 | 30 | 31 | 34 | |||
| A/Swine/SD/LY236/2016 | H1N1 | PSIQSR/GL | V | N | H | N | E | Q | A | G | A | R | E | D | H | L | I | A | N | G | ||
| A/Swine/SD/LW4/2017 | H1N1 | PSIQSR/GL | V | N | H | D | E | Q | A | G | A | R | E | D | H | L | V | A | N | G | ||
| A/Swine/SD/LW7/2017 | H1N1 | PSIQSR/GL | V | N | H | D | E | Q | A | G | A | R | E | D | H | L | V | A | N | G | ||
| A/Swine/SD/LW13/2017 | H1N1 | PSIQSR/GL | V | N | H | D | E | Q | A | G | A | R | E | D | H | L | V | A | N | G | ||
| A/Swine/SD/LW21/2017 | H1N1 | PSIQSR/GL | V | N | H | D | E | Q | A | G | A | R | E | D | H | L | V | A | N | G | ||
| A/Swine/SD/LW34/2017 | H1N1 | PSIQSR/GL | V | N | H | D | E | Q | A | G | A | R | E | D | H | L | V | A | N | G | ||
| A/Swine/SD/LW36/2017 | H1N1 | PSIQSR/GL | V | N | H | D | E | Q | A | G | A | R | E | D | H | L | V | A | N | G | ||
| A/Swine/SD/LW37/2017 | H1N1 | PSIQSR/GL | V | N | H | D | E | Q | A | G | A | R | E | D | H | L | V | A | N | G | ||
| A/Swine/SD/LW40/2017 | H1N1 | PSIQSR/GL | V | N | H | D | E | Q | A | G | A | R | E | D | H | L | V | A | N | G | ||
| A/Swine/SD/TA27/2017 | H1N1 | PSIQSR/GL | V | N | H | D | E | Q | A | G | A | R | E | D | H | L | I | A | N | G | ||
| A/Swine/HN/NY127/2017 | H1N1 | PSIQSR/GL | V | N | H | D | G | Q | A | G | A | R | E | D | H | L | V | A | N | G | ||
| A/Swine/HB/HG332/2018 | H1N1 | PSIQSR/GL | V | N | H | V | E | Q | A | G | A | R | E | D | H | L | V | A | N | G | ||
| A/Swine/HB/HG354/2018 | H1N1 | PSIQSR/GL | V | N | H | V | E | Q | A | G | A | R | E | D | H | L | V | A | N | G | ||
| A/Swine/HB/HG394/2018 | H1N1 | PSIQSR/GL | V | N | H | D | G | Q | A | G | T | Q | K | D | H | L | V | A | S | G | ||
| A/Swine/HN/NY364/2018 | H1N1 | PSIQSR/GL | V | N | H | D | E | Q | A | G | A | R | E | D | H | L | V | A | N | G | ||
| A/Swine/SD/LY396/2016 | H1N2 | PSIQSR/GL | V | N | H | D | D | R | E | G | A | R | E | D | E | R | L | V | A | N | G | |
| A/Swine/HN/NY426/2016 | H3N2 | PEKQTR/GI | T | Y | H | N | D | I | S | S | A | R | E | D | E | R | L | I | A | N | G | |
| A/Swine/HN/NY428/2016 | H3N2 | PEKQTR/GI | T | Y | H | N | D | I | S | S | A | R | E | D | E | R | L | I | A | N | G | |
| A/Swine/HN/NY430/2016 | H3N2 | PEKQTR/GI | T | Y | H | N | D | I | S | S | A | R | E | D | E | R | L | I | A | N | G | |
| A/Swine/HN/NY125/2016 | H3N2 | PEKQTR/GI | T | Y | H | N | D | I | S | S | A | R | E | D | E | R | L | I | A | N | G | |
a: Amino acid numbering refers to the HA gene of H3 subtype (GenBank accession #CY008156.1); b: Amino acid numbering refers to the NA gene of N2 subtype (GenBank accession #CY008158.1).