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. 2020 Feb 27;12(3):204. doi: 10.3390/pharmaceutics12030204

Figure 2.

Figure 2

Chemical reaction protocol for the synthesis of PNIPAM and PNIPAM-SH. (A) Synthesis of PNIPAM using reversible addition–fragmentation chain transfer (RAFT) polymerization. (B) Aminolysis for the preparation of thiol-terminated PNIPAM.