Table 1.
Sequences and targets of paralytic conotoxins from C. magus.
| Peptide | Sequence 1 | Ion-Channel Target | Reference |
|---|---|---|---|
| α-MI | GRCCHPACGKNYSC# | muscle nAChR | McIntosh 1982 [8] |
| α-MII 2 | GCCSNPVCHLEHSNLC# | neuronal nAChR | Cartier 1996 [9] |
| ω-MVIIA | CKGKGAKCSRLMYDCCTGSCRSGKC# | presynaptic Ca channel | Olivera 1987 [10] |
| μ-MIIIA | ZGCCNVPNGCSGRWCRDHAQCC# | muscle Na channel | Wilson 2011 [11] Zhang 2006 [12] |
| αM-MIIIJ | ZKCCSGGSCPLYFRDRLICPCC | muscle nAChR | Rybin 2020 [this report] |
1 Cysteine residues are bolded to highlight them; # indicates C-terminal amidation; Z indicates pyroglutamate residue. 2 α-MII is not paralytic but is shown here for comparison with α-MI.