Figure 5.

Differential expression of PRMT 5 in MDMs affected virus production. Expression of PRMT5 (a) and PRMT7 (b) mRNA in MDMs from six healthy donors. (c) MDMs from each donor were infected with the NF462 WT or NF462 ΔR strain, and virus production was measured using p24 ELISA at 0, 4, 8, and 12 days post-infection. Values shown are mean values, with error bars indicating standard deviations. Experiments were independently conducted in triplicate. Statistically significant differences are indicated by single and double asterisks (* p < 0.05 and ** p < 0.01, respectively).