Table 1.

PTH-related manifestations and beneficial effects of Parathyroidectomy.

PTH-Related Manifestations	Parathyroidectomy Effects	Ref.
Hypertension Myocardial hypertrophy	Blood pressure reduction Beneficial effect on cardiovascular mortality	[44,46]
Abnormal bone density (mainly in cortical compartment)	Improvement of bone mineral density at lumbar spine and femoral neck	[19,94]
Increase of levels of cytosolic calcium in brain synaptic terminals	Improvement of cognitive function Prevention of electroencephalogram abnormalities in uremic animals	[85,95]
Hematopoietic dysfunction Accelerate erythrocyte sedimentation rate Increase of osmotic fragility of erythrocytes	Improvement of anemia Regression of medullar fibrosis	[87,96]
Reduction of T lymphocyte proliferation and cytokine production Impairment of immunoglobulins production	Improvement on serum immunoglobulins and complement titles	[90,91]
Increase in all-cause mortality risk	Improve of survival in patients with severe secondary Hyperparathyroidism Improvement of quality of life	[14,97]