Table 3.

Concerns about 3D-printed drug products expressed by the healthcare professionals attending the focus group discussions.

Subcategory	Question or Comment (citations)
Medication safety	Is the drug substance evenly distributed within the printed dosage form?
	Does the printing technology produce accurate doses?
	Does the printed dosage form perform in a desired manner and enable the optimum therapeutic effect?
	Is it possible to check the content of each formulation with a barcode reader?
	How are the different drug products identified if they look very similar?
	How long is the shelf-life and can the medicine be stored in room temperature?
Drug administration	Can the printed dosage form be dissolved or dispersed and given through a nasogastric tube?
	For small children, it is essential that you can print a small sized dosage form.
	If the printed drug products are big in size and do not dissolve/disperse in liquid, then it is not an answer to the needs of pediatric medication.
Production and delivery on-demand	How is the logistics at the wards affected if there are many patient-specific drug products instead of commercial packages?
	What is the delivery time?
	How fast can the hospital pharmacy react to dose changes?
Costs	How much more expensive are patient-specific drug products?
	What are the costs? Is 3D printing profitable and sensible?
	Does tailoring of doses give enough advantage that it is worth paying for?