Table 1.
Functional Groups and Remarks | Vibrational Frequencies (cm−1) | |
---|---|---|
Unformulated Isoniazid | Isoniazid Loaded RDS Formulation | |
C–C–C–C and C–N–C–C torsion | 653 | 665 |
NH2 rock | 677 | 677 |
C–C–C out of plane bending | 746 | 757 |
C–C–H out of plane bending | 850 and 1022 | 850 and 1023 |
C–N–C and C–C–C in plane bending | 1063 | 1062 |
Aromatic C–N stretching | 1344 | 1330 |
C–C–H in plane bending | 1210 | 1212 |
O=C-N in plane bending | 1330 | 1333 |
C–N–H in plane bending | 1411 | 1408 |
C–C stretching | 1477 | 1471 |
C=O stretching | 1558 | 1552 |
NH2 scissoring | 1632 | 1635 |
Aromatic C–H stretching | 3052 | 3054 |
N–H stretching | 3307 | 3308 |
O–H stretching | - | 3676 |