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. 2020 Mar 23;12(3):286. doi: 10.3390/pharmaceutics12030286

Table 1.

FTIR vibrational frequencies representing formulated and unformulated isoniazid key functional groups.

Functional Groups and Remarks Vibrational Frequencies (cm−1)
Unformulated Isoniazid Isoniazid Loaded RDS Formulation
C–C–C–C and C–N–C–C torsion 653 665
NH2 rock 677 677
C–C–C out of plane bending 746 757
C–C–H out of plane bending 850 and 1022 850 and 1023
C–N–C and C–C–C in plane bending 1063 1062
Aromatic C–N stretching 1344 1330
C–C–H in plane bending 1210 1212
O=C-N in plane bending 1330 1333
C–N–H in plane bending 1411 1408
C–C stretching 1477 1471
C=O stretching 1558 1552
NH2 scissoring 1632 1635
Aromatic C–H stretching 3052 3054
N–H stretching 3307 3308
O–H stretching - 3676