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Vitreous half-life times for intravitreally administered drugs with different pharmacokinetic characteristics.
| Pharmacologic Group | Drug | Characteristics | Half-Life Time (h) | Ref. |
|---|---|---|---|---|
| Corticosteroids | Dexamethasone | Low molecular weight Water insoluble |
3.48 | [66] |
| Antibiotics | Ceftizoxime | Low molecular weight Water soluble |
5.70 | [67] |
| Somatostatin analogues | Octreotide acetate | High molecular weight Water soluble |
16.00 | [68] |
| Antiviral | ISIS 2922 | High molecular weight Water soluble |
62.00 | [69] |
