Table 3.
Meta-analyses regarding the impact of subclinical hypothyroidism and subclinical hyperthyroidism on bone health.
| Bone-Related Outcome | Number of Patients | Conclusion | Year | References |
|---|---|---|---|---|
| Subclinical hypothyroidism | ||||
| Osteoporosis Fracture risk |
313,557 | Subclinical hypothyroidism has no impact on fracture risk. | 2019 | [43] |
| Fracture risk | 314,146 | Subclinical hypothyroidism is not associated with an increased risk of fracture. | 2016 | [44] |
| Fracture risk | 70,298 | Subclinical hypothyroidism is not associated with an increased risk of fractures. | 2015 | [45] |
| Subclinical hyperthyroidism | ||||
| Osteoporosis Fracture risk |
313,557 | Subclinical hyperthyroidism could increase the risk of fractures and decrease BMD. | 2019 | [40] |
| Osteoporosis | 5458 | Subclinical hyperthyroidism is associated with lower BMD. | 2018 | [46] |
| Fracture risk | 314,146 | Subclinical hyperthyroidism is associated with an increased risk of fracture. | 2016 | [44] |
| Fracture risk | 70,298 | Subclinical hyperthyroidism is associated with an increased risk of fractures. | 2015 | [45] |