Table 1.

The conventional use and route of small molecule drugs which are also under investigation for potential positive effects in wound-healing resolution and reducing fibrosis.

Drug	Conventional Use	Conventional Route	Wound Resolution Indications
Deferoxamine (DFOA)	Treating iron/aluminum toxicity	SQ, IM, IV	Decreases oxidative stress and necrosis [16] Enhances neovascularization [17] Reduces interstitial renal fibrosis [18]
Metyrapone (MTP)	Inhibition of adrenal steroidgenesis	PO	Enhances epithelialization [19,20]
Rifampicin (RIF)	Antibiotic activity	PO, IV	Ulcer resolution [21] Immunomodulatory [22,23]
Pyrvinium pamoate (PYR)	Anthelmintic activity	PO	Wnt inhibition [24] Inhibits fibroblast survival [25]