Table 3.
Advantages | Disadvantages |
---|---|
Biocompatibility | Physical instability in liquid state |
Versatility for drug encapsulation | Lysolipid formation by chemical degradation |
Flexibility of membrane components | Drug leakage |
Capability of surface modification | Disruption in the stomach |
Proposed enhanced permeation | Low permeability of intact liposome in the GI tract |
Modifiable pharmacokinetic behavior | Difficulty in mass production and quality control |