Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
(A) OAT1- and (B) OAT3-mediated uptake of DWP16001. Concentration dependent uptake of DWP16001 was measured for 5 min into HEK293-mock cells and HEK293 cells expressing OAT1 and OAT3. The transporter-mediated uptake rate was obtained by subtracting the uptake in HEK293-mock cells (passive diffusion) from those in HEK293 cells expressing OAT1 and OAT3 (total uptake). Each data point represents the means ± standard deviation from triplicate experiments.
