Table 1.
Statistical analysis of data shown in Figure 2. Differences were calculated with respect to the intraocular pressure measured in rats instilled with saline.
| Time | 0.4% Melatonin in Saline | 0.4% Melatonin in Nanomicelles |
|---|---|---|
| 0 | 3.7% | 2.4% |
| 15 min | −29.4% 1 | −31.8% 1 |
| 30 min | −7.1% | −36.4% 1,2 |
| 1 h | −8.3% | −9.5% |
| 2 h | −6.9% | −9.3% |
| 3 h | −3.5% | −4.7% |
| 4 h | −3.5% | −7.1% |
| 6 h | 3.7% | 2.4% |
| 8 h | 3.7% | 1.3% |
1p < 0.001 vs. saline and 2 p < 0.001 vs. 0.4% melatonin in saline. Statistical analysis was performed using two-way ANOVA followed by Bonferroni’s multiple comparison post-test.