Table 3.

Statistical analysis of data shown in Figure 4. Differences were calculated with respect to the intraocular pressure measured in rats instilled with saline.

Time	0.4% Melatonin/Agomelatine	0.4% Melatonin/Agomelatine + 0.15% Lipoic Acid
0	4.7%	8.3%
15 min	−17.2% 1	−23.6% 2
30 min	−33.9% 2	−37.3% 2
1 h	−50.3% 2	−50.8% 3
2 h	−52.9% 2	−45.9% 2
3 h	−55.5% 2	−52.0% 2
4 h	−52.0% 2	−54.3% 2
6 h	−26.0%	−49.7% 2,3
8 h	−6.9%	−38.3% 2,3

¹p = 0.05 vs. basal; ² p < 0.001 vs. basal; ³ p < 0.001 vs. 0.4% melatonin and agomelatine. Statistical analysis was performed using two-way ANOVA followed by Bonferroni’s multiple comparison post-test.