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Pictorial representation of hybridization (a) on a DNA-modified gold nanoparticle and (b) in solution. Hybridization of a complement bearing a dangling end increases the hydrodynamic radius of the nanoparticle and can be followed by dynamic light scattering. X and Y represent two different families of oligonucleotides. Reprinted with the permission from [102]. Copyright 2015 American Chemical Society.
