Table 1.

Main applications of nanoparticles (NPs) drug delivery systems. CNS: central nervous system.

Applications of NPs Drug Delivery Systems	Advantages
Tumors	Passive targeting promoted by enhanced permeability and retention (EPR) effect: accumulation on target site is favored
Diabetes	Less-invasive route for the delivery of insulin and improvement in the drug delivery
Cardiovascular Diseases	Development of regenerative medicine and of the possibility to manage this kind of disease
CNS Injuries	Possibility to overcome biological barriers, reaching the CNS and having a less-invasive delivery system