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. 2020 Mar 22;10(3):171. doi: 10.3390/diagnostics10030171

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Screening and verification of diagnostic markers. (A) Least absolute shrinkage and selection operator (LASSO) logistic regression algorithm to screen diagnostic markers. Different colors represent different genes. (B) Support vector machine-recursive feature elimination (SVM-RFE) algorithm to screen diagnostic markers. (C) Venn diagram shows the intersection of diagnostic markers obtained by the two algorithms. (D) The ROC curve of the diagnostic efficacy verification after fitting two diagnostic markers to one variable.