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. 2020 Mar 26;158(1):195–205. doi: 10.1016/j.chest.2020.03.032

Table 5.

Multivariate Analysis of Independent Risk Factors for Differentiating COVID-19 From H1N1

Variable Univariate Analysis
Multivariate Analysis
OR 95% CI P Value OR 95% CI P Value
Age 0.928 0.092-0.956 < .001 0.908 0.843-0.978 .011
Cardiovascular disease 0.260 0.107-0.628 .003 0.631 0.083-4.577 .649
Septic shock 0.334 0.146-0.766 .010
Respiratory rate 1.018 0.983-1.054 .325
Heart rate 1.021 1.004-1.039 .015
SOFA score 1.820 1.462-2.266 < .001 2.263 1.124-3.574 .006
APACHE II score 1.136 1.062-1.214 < .001 1.124 0.932-1.355 .221
Fatigue 0.135 0.064-0.285 < .001 0.117 0.021-0.941 .013
Sputum 3.215 1.567-6.597 .001 9.576 1.729-64.711 .011
GI symptoms 0.122 0.044-0.339 < .001 0.100 0.009-0.984 .044
Myalgia 0.330 0.148-0.736 .007 1.832 0.512-6.555 .352
Prothrombin time 0.673 0.555-0.817 < .001 0.627 0.458-0.858 .004
APTT 0.986 0.954-1.019 .409
D-dimer 1.036 0.993-1.080 .100
AST 1.035 1.021-1.049 < .001 1.021 0.998-1.044 .074
Direct bilirubin 1.155 1.055-1.265 .002
Lactate dehydrogenase 1.004 1.002-1.005 < .001 1.007 1.000-1.014 .025
Troponin I 1.517 0.883-2.605 .131
CD3+ T lymphocyte 1.004 1.002-1.006 .001
CD4+CD3+ T lymphocyte 1.007 1.003-1.010 < .001
Ground-glass opacity 0.048 0.016-0.145 < .001 0.086 0.015-0.490 .006
Consolidation 2.053 1.039-4.056 .038 4.956 1.518-16.176 .008

APTT = activated partial thromboplastin time. See Table 1 and 3 legends for expansion of abbreviations.