Table 2.
Outcomes comparing severe cases and non-severe cases of COVID-19.
Outcomes | Critical illness |
Non-critical illness |
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---|---|---|---|---|---|---|---|---|
No. reports | No. patients | Prevalence% (95%CI) | I2 (%) | No. reports | No. patients | Prevalence% (95%CI) | I2 (%) | |
Clinical symptoms | ||||||||
Fever | 6 | 364 | 80.8 (41.1–100.0) | 97 | 6 | 1299 | 71.2 (23.8–99.9) | 98 |
Cough | 6 | 364 | 65.6 (51.7–78.2) | 67 | 6 | 1299 | 56.7 (39.5–73.2) | 88 |
Sore throat | 3 | 245 | 16.7 (0.0–53.2) | 77 | 3 | 1135 | 11.2 (3.5–22.4) | 63 |
Increased sputum production | 3 | 222 | 32.1 (15.6–51.0) | 19 | 3 | 1065 | 31.4 (23.1–40.5) | 14 |
Shortness of breath | 6 | 364 | 49.2 (21.5–77.2) | 90 | 5 | 1216 | 13.3 (2.2–30.9) | 85 |
Myalgia | 5 | 351 | 17.6 (8.2–29.5) | 57 | 5 | 1201 | 20.8 (10.0–33.9) | 85 |
Fatigue | 4 | 299 | 41.2 (5.2–84.0) | 92 | 5 | 1201 | 34.5 (13.2–59.6) | 93 |
Diarrhea | 4 | 234 | 7.6 (0.0–24.0) | 55 | 3 | 1053 | 4.3 (0.1–12.5) | 54 |
Headache | 4 | 274 | 11.3 (0.1–33.9) | 74 | 5 | 1172 | 11.9 (5.8–19.7) | 53 |
Laboratory findings | ||||||||
Leucocytes (↑) | 2 | 186 | 27.7 (0.0–100.0) | 91 | 3 | 838 | 9.3 (0.0–1.0) | 67 |
Leucocytes (↓) | 3 | 216 | 33.7 (0.00–95.7) | 92 | 3 | 957 | 27.2 (24.3–30.1) | 0 |
Lymphocytes (↓) | 3 | 203 | 81.5 (18.9–100.0) | 94 | 4 | 883 | 59.6 (32.2–84.2) | 99 |
Platelets (↓) | 2 | 169 | 32.3 (0.0–100.0) | 93 | 3 | 740 | 16.4 (0.0–1.0) | 88 |
Aspartate aminotransferase (↑) | 2 | 155 | 46.1 (0.0–100.0) | 56 | 3 | 653 | 15.5 (0.0–50.8) | 55 |
Creatinine (↑) | 2 | 151 | 6.4 (0.0, 100.0) | 57 | 2 | 642 | 2.3 (0.0, 97.1) | 76 |
Creatine kinase (↑) | 2 | 134 | 28.6 (0.0–100.0) | 76 | 3 | 563 | 16.7 (0.0–1.0) | 96 |
Lactate dehydrogenase (↑) | 3 | 173 | 62.7 (55.7–100.0) | 83 | 3 | 818 | 28.1 (0.0, 100.0) | 99 |
C-reactive protein (↑) | 2 | 171 | 40.3 (0.0–100.0) | 99 | 5 | 1026 | 51.2 (38.6–63.8) | 71 |
D-dimer (↑) | 2 | 109 | 59.6 (50.2–68.7) | 0 | 1 | 451 | 43.2 (38.7–47.8) | 0 |
Procalcitonin (↑) | 3 | 165 | 35.7 (0.0–100.0) | 95 | 4 | 660 | 55.2 (0.0–33.8) | 95 |
Chest CT findings | ||||||||
Bilateral pneumonia | 2 | 186 | 91.0 (0.0–100) | 83 | 1 | 926 | 39.7 (36.6–42.9) | 0 |
Complications | ||||||||
ARDS | 4 | 315 | 38.2 (3.2–83.0) | 96 | 2 | 130 | 4.3 (2.8, 6.0) | 0 |
Cardiac failure | 4 | 155 | 17.1 (1.5–42.2) | 78 | 2 | 130 | 1.9 (0.0, 26.0) | 0 |
Shock | 3 | 222 | 17.4 (0.0, 61.5) | 87 | . | . | . | . |
Renal insufficiency | 5 | 328 | 9.8 (0.1–28.7) | 87 | . | . | . | . |
ARDS=Acute Respiratory Distress Syndrome.