Skip to main content
. 2020 Apr 10;80(6):656–665. doi: 10.1016/j.jinf.2020.03.041

Table 2.

Outcomes comparing severe cases and non-severe cases of COVID-19.

Outcomes Critical illness
Non-critical illness
No. reports No. patients Prevalence% (95%CI) I2 (%) No. reports No. patients Prevalence% (95%CI) I2 (%)
Clinical symptoms
 Fever 6 364 80.8 (41.1–100.0) 97 6 1299 71.2 (23.8–99.9) 98
 Cough 6 364 65.6 (51.7–78.2) 67 6 1299 56.7 (39.5–73.2) 88
 Sore throat 3 245 16.7 (0.0–53.2) 77 3 1135 11.2 (3.5–22.4) 63
 Increased sputum production 3 222 32.1 (15.6–51.0) 19 3 1065 31.4 (23.1–40.5) 14
 Shortness of breath 6 364 49.2 (21.5–77.2) 90 5 1216 13.3 (2.2–30.9) 85
 Myalgia 5 351 17.6 (8.2–29.5) 57 5 1201 20.8 (10.0–33.9) 85
 Fatigue 4 299 41.2 (5.2–84.0) 92 5 1201 34.5 (13.2–59.6) 93
 Diarrhea 4 234 7.6 (0.0–24.0) 55 3 1053 4.3 (0.1–12.5) 54
 Headache 4 274 11.3 (0.1–33.9) 74 5 1172 11.9 (5.8–19.7) 53
Laboratory findings
 Leucocytes (↑) 2 186 27.7 (0.0–100.0) 91 3 838 9.3 (0.0–1.0) 67
 Leucocytes (↓) 3 216 33.7 (0.00–95.7) 92 3 957 27.2 (24.3–30.1) 0
 Lymphocytes (↓) 3 203 81.5 (18.9–100.0) 94 4 883 59.6 (32.2–84.2) 99
 Platelets (↓) 2 169 32.3 (0.0–100.0) 93 3 740 16.4 (0.0–1.0) 88
 Aspartate aminotransferase (↑) 2 155 46.1 (0.0–100.0) 56 3 653 15.5 (0.0–50.8) 55
 Creatinine (↑) 2 151 6.4 (0.0, 100.0) 57 2 642 2.3 (0.0, 97.1) 76
 Creatine kinase (↑) 2 134 28.6 (0.0–100.0) 76 3 563 16.7 (0.0–1.0) 96
 Lactate dehydrogenase (↑) 3 173 62.7 (55.7–100.0) 83 3 818 28.1 (0.0, 100.0) 99
 C-reactive protein (↑) 2 171 40.3 (0.0–100.0) 99 5 1026 51.2 (38.6–63.8) 71
 D-dimer (↑) 2 109 59.6 (50.2–68.7) 0 1 451 43.2 (38.7–47.8) 0
 Procalcitonin (↑) 3 165 35.7 (0.0–100.0) 95 4 660 55.2 (0.0–33.8) 95
Chest CT findings
 Bilateral pneumonia 2 186 91.0 (0.0–100) 83 1 926 39.7 (36.6–42.9) 0
Complications
 ARDS 4 315 38.2 (3.2–83.0) 96 2 130 4.3 (2.8, 6.0) 0
 Cardiac failure 4 155 17.1 (1.5–42.2) 78 2 130 1.9 (0.0, 26.0) 0
 Shock 3 222 17.4 (0.0, 61.5) 87 . . . .
 Renal insufficiency 5 328 9.8 (0.1–28.7) 87 . . . .

ARDS=Acute Respiratory Distress Syndrome.