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. 2020 Apr 6;15(2):138–148. doi: 10.18502/jovr.v15i2.6730

Table 2.

Predicted variant impact on LOX protein conformation analyzed by PMUT, SIFT, and PolyPhen2 algorithms. Allelic frequencies are indicated.


Residue PMUT PolyPhen2 SIFT TGP frequency
R158Q 0.11 0.000 0.21 0.157 (16%)
T392P 0.68 0.087 0.02 ND
TGP, 1000 Genome project; ND, not described