Table 3.
Demographic, clinical, and pulmonary function variables in ≥4% oxygen Desaturators vs. Nondesaturators during the 6-minute walk Test.
| Variable | Nondesaturators (Δ SpO2 > −3%) N = 224 (70%) |
Desaturators (Δ SpO2 ≤ −4%) N = 95 (30%) |
p-Value |
|---|---|---|---|
| Age, years | 52.92 ± 14.11 | 57.96 ± 13.20 | 0.003 |
| Sex, no. (%) | 0.697 | ||
| Male | 82 (68) | 38 (32) | |
| Female | 142 (72) | 57 (28) | |
| Race, no. (%) | 0.364 | ||
| White | 53 (29) | 130 (71) | |
| Black | 41 (32) | 88 (68) | |
| Hispanic | 1 (100) | 0 (0) | |
| Asian | 1 (100) | 0 (0) | |
| Other | 0 (0) | 1 (100) | |
| BMI (kg/m2) | 29.42 ± 8.10 | 30.14 ± 8.19 | 0.472 |
| Obstruction (FEV1/FVC<70%), no. (%) | 39 (40) | 59 (60) | 0.01 |
| Restriction (TLC < 80%), no. (%) | 33 (34.4) | 63 (65.6) | 0.238 |
| Combined obstruction and restriction, no. (%) | 3 (3.2) | 2 (1.8) | 0.444 |
| FVC, L | 2.88 ± 0.9 | 92.43 ± 1.05 | 0.001 |
| FVC, %predicted | 78.05 ± 16.51 | 68.55 ± 24.84 | 0.002 |
| FEV1, L | 2.10 ± 0.82 | 1.59 ± 0.74 | <0.001 |
| FEV1, %predicted | 72.72 ± 21.55 | 57.64 ± 21.85 | <0.001 |
| FEV1/FVC ratio | 73.14 ± 15.80 | 67.39 ± 21.38 | 0.027 |
| TLC, L | 4.94 ± 1.45 | 4.55 ± 1.55 | 0.05 |
| TLC, % predicted | 90.89 ± 20.44 | 85.08 ± 28.09 | 0.094 |
| RV, L | 2.10 ± 1.00 | 2.16 ± 1.10 | 0.636 |
| RV, %predicted | 114.85 ± 50.58 | 114.89 ± 58.69 | 0.996 |
| DLCO, mL/min/mmHg | 15.28 ± 5.92 | 9.77 ± 4.35 | <0.001 |
| DLCO, %predicted | 68.54 ± 24.81 | 42.51 ± 19.25 | <0.001 |
| Airway resistance, cmH2O/L/sec | 1.95 ± 1.33 | 2.20 ± 1.33 | 0.144 |