Figure 3.

TAB and GMB suppressed mRNA expression of MMPs in UVB-irradiated HaCaT keratinocytes. HaCaT keratinocytes were pre-treated with the indicated concentration for 24 h in serum-free media, and incubated for 6 h followed by UVB (50 mJ/cm²) irradiation treated with TNF-α (10 ng/mL), (A) MMP-1 and (B) MMP-9 mRNA levels were measured by qRT-PCR. Retinol (1 and 5 μM) and adenosine (1 and 5 μM) were used as positive control. ^### p < 0.001 versus the control group; * p < 0.05, ** p < 0.01, and *** p < 0.001 versus the UVB-irradiated group. MMP-1, matrix metalloproteinase-1; MMP-9; matrix metalloproteinase-9.