Table 1.

Recent studies of immunological profiles in community-acquired pneumonia.

Study	Immunological Profile	Clinical Correlate
Bermejo-Martin et al. [77] (n = 4396; CAP immunocompetent)	Lymphocytes (<724 cells/mm3) L-CAP phenotype	Increased ICU admission
		More complications
		Increased 30-day mortality
Mendez et al. [78] (n = 217, CAP immunocompetent)	L-CAP phenotype present: CD4+ depletion, higher inflammatory response, and low IgG2 levels	Increased severity of pneumonia at presentation
		Increased treatment failure
		Increased 30-day mortality
Güell et al. [79] (n = 710; CAP admitted to ICU)	Lymphopenia <675 cells/mm3 or <501 cells/mm3	2.32- and 3.76-fold risk of mortality in patients with or without septic shock
	Neutrophils <8850 cells/mm3	3.6-fold risk of mortality

Abbreviations: CAP: community-acquired pneumonia; ICU: intensive care unit; L-CAP: lymphopenic community-acquired pneumonia.