Figure 7.

Influence of typical antipsychotics (haloperidol), atypical antipsychotics (olanzapine, ziprazidone, risperidone), MAO inhibitor antidepressants (phenelzine, pargyline), tricyclic antidepressants (opipramol), and various inhibitors (harmine, semicarbazide) on [¹⁴C]-tyramine and [¹⁴C]-benzylamine oxidation by human white adipose tissue. Homogenates (approximately 100 µg protein/100 µL) were preincubated for 15 min with the indicted agents, then incubated for 30 min in the presence of 0.5 mM [¹⁴C]-tyramine (left panel) or 0.5 mM [¹⁴C]-benzylamine (right panel). For each amine, results are expressed as respective oxidation without added agent (100%). Each point is mean ± SEM of four to nine observations.