Table 2. The parent–child-pairs OTU overlap and hypergeometric p-value.

The samples with replicates were summarized by taking average (avg) of the replicates (Figs. S1–S3). The change in sample name after summarizing is mapped to its original pedigree number.

	Pedigree number	Age of child (y)	Age of parent (y)	Overlap (number of OTUs)	Hypergeometric p-value
Nuclear family A
CoreA_Mother–coreA_daughter1_avg (Fig. S1)	2 4	51	76	54	0.006811284
CoreA_Mother–coreA_daughter2 (Fig. S1)	2 5	50	76	39	NS
CoreA_Mother–coreA_daughter3 (Fig. S2)	2 6	53	76	52	4.593393e-05
CoreA_father–coreA_daughter1_avg (Fig. S1)	1 4	51	82	52	3.138095e-05
CoreA_father_avg–coreA_daughter2 (Fig. S1)	1 5	50	82	37	NS
CoreA_father_avg–coreA_Daughter3_avg (Fig. S2)	1 6	53	82	46	0.0001144497
Nuclear family B
CoreB_mother_avg–coreB_daughter_avg (Fig. S3)	4 7	22	51	60	2.649257e-06
CoreB_mother_avg–coreB_Son (Fig. S3)	4 8	20	51	62	NS
CoreB_father_avg–coreB_daughter_avg (Fig. S3)	3 7	22	54	39	0.0005486819
CoreB_father_avg–coreB_Son (Fig. S3)	3 8	20	54	42	NS