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. 2018 Sep 28:539–547. doi: 10.1016/B978-0-323-55228-8.00077-1

TABLE 77.2.

Select Chemical Restraint Agents Used in African Wild Dogs (Lycaon pictus)

Drug Combination (mg/kg) IM Reversal Agent (mg/kg) IM Comments
Medetomidine (0.025–0.04)
Ketamine (2.5–3)
± Midazolam (0.1–0.15)
± Butorphanol (0.1–0.2)
Atipamezole (0.14–0.24)
± Flumazenil (0.01–0.05)
± Naloxone (0.02)
Excellent muscle relaxation, quick recovery

Medetomidine (0.03)
Midazolam (0.3), Butorphanol (0.3)
Completely reversible

Dexmedetomidine (0.025), Ketamine (3), Midazolam (0.15) Atipamezole, flumazenil Generally larger dart volume

Ketamine (2–4), Midazolam (0.15–0.3), Butorphanol (0.3–0.4),
± Supplemental Propofol (0.4–0.5 IV) or Gas anesthesia
Flumazenil, naloxone Suggested alternative for cardiac cases

Tiletamine-Zolazepam
(Telazol) (2–5)
Reliable plane of anesthesia, prolonged recoveries

IM, Intramuscular; IV, intravenous.