FIGURE 2-38.
Mesenchymal neoplasm. Tissue imprint. Dog. Round to oval nuclei, anisokaryosis, high nuclear-to-cytoplasmic ratio, prominent and variably shaped nucleoli, and individualized cells with poorly distinct cytoplasmic borders suggest a malignant mesenchymal neoplasm. This lesion is from a gum mass with a histologically confirmed diagnosis of amelanotic melanoma. One cell in the center contains small amounts of melanin pigment granules. (Aqueous-based Wright; HP oil.)