Table 10.2.
Properties of bovine immunoglobulins
| IgG1 | IgG2 | IgA | SIgA | IgM | |
|---|---|---|---|---|---|
| Physico-chemical | |||||
| Molecular weight (kDa) | 146–163 | 146–154 | 160 | 385–430 | 900 |
| Heavy chain | 56–59 | 54–59 | 61–63 | 62–76 | |
| Heavy chain type | γ1 | γ2 | α | α | μ |
| Number of H- and L-chains | 2 | 2 | 2 | 4 | 10 |
| Structure | Monomer | Monomer | Monomer | Dimer | Pentamer |
| Immunological | |||||
| Opsonization | +++ | + | 0 | 0 | +++ |
| Complement fixation | ++ | + | 0 | 0 | +++ |
| Agglutination | + | + | ++ | ++ | +++ |
0 = no activity, + = low activity, ++ = moderate activity, +++ = strong activity.
Data modified from Marnila and Korhonen (2002).