Table 58-4.
Efficacy of Various Treatments for Chronic Colitis in Dogs and Cats Based on Published Case Series
| Source | Number of Animals | Treatment Evaluated | Success Rate |
|---|---|---|---|
| Cats | |||
| Nelson et al., 198429 | 6 Cats | Homemade diet (boiled lamb and rice), then switched to highly digestible commercial diet. SS × 3 weeks in 1 cat with NR to commercial diet. | CR in 6 cats fed homemade diet. Rec in 2 cats when switched to highly digestible diet. Both controlled with homemade diets, 1 required SS for 3 wk. |
| Dennis et al., 199330 | 13 Cats available for follow up | F (high F diet or addition of F to diet) in 8 of 10 cats with CR or PR, highly digestible diet in 2/7. CR cats received T and/or P initially, which was then d/c. All cats with CR maintained on diet alone. Cats with PR on P or SS as needed. | CR in 7 cats within 6 to 50 mo. PR in 3 cats. No change in one cat. Two cats with severe disease euthanized without treatment. |
| Dogs | |||
| Nelson et al., 198839 | 13 Dogs | Diet, initially homemade (cottage cheese and rice), followed by commercial novel antigen or low-residue diet. No medication. | CR to homemade diet in all dogs within 3 days to 6 wk. Rec in 2 of 13 after switch to commercial novel antigen or low-residue diet. Rec in 9 of 11 after exposure to pretreatment diet. |
| Simpson et al., 199440 | 11 Dogs | Diet (commercial restricted antigen), initially SS in 9 dogs, d/c after resp of clinical signs. No F supplementation. | SS could be d/c after 1 mo in 3 of 9, 2 mo. in 8 of 9 but had to be resumed in 1 dog. Improvement in stool consistency, fecal mucus, and fecal blood, but not in frequency of defecation in all dogs. |
| Leib, 200031 | 27 Dogs available for follow up | F (psyllium) added to various commercial or homemade (low-fat, low-residue or novel protein) diet. | Response excellent in 17, very good in 6, good in 3, and poor in 1 dog. Fiber could be d/c in 5 of 11 dogs, and special diet could be d/c in 5 of 7 dogs. |
| Allenspach et al., 200728 | 30 Dogs | Diet (commercial novel antigen), P if NR to diet after 10 days. | CR in 28, NR or PR in 2. No data about resp to P in these 2 dogs. |
CR, complete remission; D, diet; d/c, discontinued; F, fiber; NR, no response; P, prednisone; PR, partial remission; rec, recurrence; resp, response; SS, sulfasalazine; T, tylosin