TABLE 49.1.
Normal Lymphocyte Subsets With Agea
| Cord Blood | 2 Days–11 Months | 1–6 Years | 7–17 Years | 18–70 Years | |
|---|---|---|---|---|---|
| Total lymphocyte count (×103 cells/mL) | 5.4 (4.2–6) | 4.1 (2.7–5.4) | 3.6 (2.9–5.1) | 2.4 (2.0–2.7) | 2.1 (1.6–2.4) |
| CD4+ T cells (%) | 35 (28–42) | 41 (38–50) | 37 (30–40) | 37 (33–41) | 42 (38–46) |
| CD45Ra+ in CD4+ (naive T cells)b | 91 (82–97) | 81 (66–88) | 71 (66–77) | 61 (55–67) | 40 (32–49) |
| CD8+ T cells (%) | 29 (26–33) | 21 (18–25) | 29 (25–32) | 30 (27–35) | 35 (31–40) |
| B cells (%) | 20 (14–23) | 23 (19–31) | 24 (21–28) | 16 (12–22) | 13 (11–16) |
| NK cells (%) | 20 (14–30) | 11 (8–17) | 11 (8–15) | 12 (9–16) | 14 (10–19) |
NK, Natural killer.
a
Values are median, with ranges from the 25th to 75th percentiles.
b
Naive T cells expressed as a percentage of CD4+ T cells.