. 2017 Jul 21:3–15. doi: 10.1016/B978-0-323-44585-6.00002-3

TABLE 2.5.

Applications of the Polymerase Chain Reaction to Microbial Detection in Tissues

Organism	Pathologic Process
Aspergillus	Invasive aspergillosis²¹

Human papillomavirus	Cervical HSIL and LSIL, HPV-positive squamous cell carcinoma of the oropharynx

Herpes virus	Herpes encephalitis (CSF or brain biopsy)

Mycobacteria	Necrotizing granulomatous inflammation

Bartonella	Cat-scratch disease or bacillary angiomatosis

Enterovirus, adenovirus, influenza A virus	Viral myocarditis²⁰

CSF, Cerebrospinal fluid; HPV, human papillomavirus; HSIL, high-grade squamous intraepithelial lesion; LSIL, low-grade squamous intraepithelial lesion.