TABLE 8-1.
Acceleration of Routine Vaccine Schedule for Travel
| Vaccine | Earliest Age for First Dose | Minimum Interval Between Doses |
|---|---|---|
| Combined hepatitis A and Ba | 1 year | 1 week, 2 weeks between 2nd and 3rd doses (booster after 1 year) |
| Hepatitis A | 1 year | 6 monthsb |
| DTaP | 6 weeks | 4 weeks, 6 months between 3rd and 4th doses |
| IPV | 6 weeks | 4 weeks |
| OPV | Birth | 4 weeks |
| Hib (conjugate) | 6 weeks | 4 weeks (booster after 12 months of age) |
| Hepatitis B | Birth | 4 weeks, 8 weeks between 2nd and 3rd doses (3rd dose should be given ≥16 weeks after 1st dose) |
| PCV13 | 6 weeks | 4 weeks, 8 weeks between 3rd and 4th doses (after 12 months of age) |
| Measles | 6 months followed by MMR at 12 months and at 4 to 6 years of age | 4 weeks |
| MMR | 12 months | 4 weeks |
| Rotavirusc | 6 weeks | 4 weeks |
| Varicella | 12 months | 4 weeks if ≥13 years of age 3 months if <13 years of age |
DTaP, diphtheria, tetanus, acellular pertussis; Hib, Haemophilus influenzae b; IPV, inactivated polio virus; MMR, measles, mumps, rubella; OPV, oral polio virus; PCV13, pneumococcal conjugate. Regular immunization schedule should be reinstituted upon return from the endemic area.
Combined hepatitis A and B accelerated schedule is an off-label use for children.
Hepatitis A booster does not need to be given as an accelerated schedule as seroconversion rate following the first dose is high. The second dose can be given any time after 6 months to induce long-lasting immunity.
For rotavirus vaccine, the maximum age for the first dose is 14 weeks and 6 days, and the maximum age for the last dose is 8 months and 0 days.