Table 13-2.
Vaccine Class | Virus | Comments |
---|---|---|
Live virus vaccines | Adenovirus Chickenpox Measles Mumps Poliovirus (Sabin vaccine) Rotavirus Rubella Smallpox (variola) Yellow fever |
Active immunization using avirulent attenuated strains Effective at inducing antibodies and cytotoxic lymphocyte responses |
Killed virus vaccines | Hepatitis A Influenza Poliovirus (Salk vaccine) Rabies |
Active immunization using heat or chemically inactive virus particles Vaccination may be combined with other viruses (polyvalent) |
Virus-like particles | Human papillomavirus | Immunization using particles assembled from recombinant coat proteins |
Subunit vaccines | Adenovirus | Active immunization using purified proteins |
Polypeptide vaccines | Hepatitis B | Active immunization using synthesized polypeptide protein sequences |
DNA vaccines (evaluation only) | HIV Influenza |
Experimental Useful for induction of cytotoxic T-lymphocyte response |
Passive antibodies | Hepatitis A Hepatitis B Measles Mumps Rabies Respiratory syncytial virus Rubella Varicella-zoster |
Injected purified antibodies obtained from another source Short-lived function with little value when given after disease onset |
HIV, human immunodeficiency virus.