Table 11-6.

Example of Causes for Lookback Notification

Item	Lookback Initiated If
HBsAg	Repeatedly reactive HBsAg confirmed positive by neutralization (or neutralization not done) is found in a subsequent donation whose prior test results were nonreactive OR Repeatedly reactive HBsAg, negative neutralization AND repeatedly reactive HBcore is found in a subsequent donation whose prior test results were nonreactive
HBcore	Repeatedly reactive anti-HBcore, and the test result of the second test method is reactive in a subsequent donation whose prior test results were nonreactive OR Repeatedly reactive anti-HBcore and repeatedly reactive HBsAg in a subsequent donation whose prior test results were nonreactive
HTLV-I/II	Repeatedly reactive anti-HTLV-I/II and the second test result is repeatedly reactive or not performed is found in a subsequent donation, whose prior test results were nonreactive or not previously tested
Anti-HIV-1,2	Repeatedly reactive anti-HIV-1,2 confirmed positive HIV-1 Western Blot OR HIV-2 EIA reactive found in a subsequent donation not previously tested or whose prior test results were nonreactive
HIV-1 NAT	NAT reactive AND HIV-1 Western Blot (or IFA) indeterminate positive or HIV-2 EIA reactive is found in a subsequent donation whose prior test results were nonreactive or prior donation was not tested
Anti-HCV	Repeatedly reactive anti-HCV with a supplemental test result of positive, indeterminate OR no supplemental test performed found in a subsequent donation whose prior donation was not previously tested with the currently licensed test, or whose prior test results were nonreactive
HCV NAT	NAT reactive with a supplemental test result of positive, indeterminate OR no supplemental test performed found in a subsequent donation whose prior donation was not previously tested, or whose prior test results were nonreactive
WNV	Current donation sample has a reactive WNV NAT. Relevant collections include those occurring between 120 days prior to the date of the reactive test and 120 days after the date of the reactive test. Donor reports a diagnosis of West Nile virus occurring between 14 days prior to the onset of illness and up to and including 120 days subsequent to the onset of illness or diagnosis, whichever is the later date. Donor reports unexplained febrile illness with headache or symptoms suggestive of WNV infection between June 1 and November 30, and Medical Director has determined this represents likely infection by WNV. A report is received regarding possible transmission of WNV by a blood component received within the 120 days prior to the onset of symptoms, or a WNV-fatality in a transfused recipient. Prompt quarantine and retrieval for in-date components collected from the donor of suspect donation in the period between 120 days before the suspect donation and up to and including 120 days after the suspect donation must be performed.
CJD or vCJD Risk factors	Subsequent to donation, the donor: is diagnosed with Creutzfeldt-Jakob disease indicates a family history of Creutzfeldt-Jakob disease acknowledges receipt of human pituitary-derived growth hormone (HGH) acknowledges receipt of a dura mater transplant indicates having spent a total time of 3 months or more in the United Kingdom from 1980 through 1996 indicates receipt of injecTable products from cattle in BSE-endemic countries acknowledges spending a total time of 5 years or more in Europe, including time spent in the UK If a member of the U.S. military, a civilian military employee or a dependent of a member of the US military and spent a total of 6 months or more associated with a military base in any of the following countries: From 1980 through 1990 in Belgium, the Netherlands, or Germany From 1980 through 1996 in Spain, Portugal, Turkey, Italy, or Greece
AIDS-related	If a donor implicated in the investigation of transfusion-associated AIDS has a reactive test result for anti-HIV-1, 2 and/or HIV-1 antigen. If information is received that a patient with AIDS has previously donated blood.
High-risk behavior (e.g., travel, vaccination malaria, tattoo, blood exposure)	Postdonation information becomes available regarding a donor who would have been deferred had the information been known at the time of donation.