Table 3.
Clinical Characteristics in Normal and High Visceral Abdominal Fat
| Normal VAF(<1658.5 cm3) | High VAF (≥1658.5 cm3) | p | |
|---|---|---|---|
| Age years | 55.97±10.70 | 58.96±9.60 | 0.30 |
| Gender | |||
| Men n (%) | 11 (16.7) | 10 (38.5) | 0.025*** |
| Women n (%) | 55 (83.3) | 16 (61.5) | |
| BMI kg/m2 | 26.89±3.83 | 33.50±5.45 | <0.001* |
| Waits-hip ratio | 0.87±0.08 | 0.92±0.52 | 0.003* |
| Hypertension n (%) | 12 (18.2) | 18 (69.2) | <0.001*** |
| Dyslipidemia n (%) | 19 (28.8) | 10 (38.5) | 0.39 |
| T2DM n (%) | 7 (10.6) | 8 (30.8) | 0.020*** |
| Inflammatory Cytokines | |||
| TNF-α pg/mL | 775.07±80.36 | 656.11±55.62 | 0.90 |
| IL-6 pg/mL | 595.06±122.85 | 864.45±227.39 | 0.75 |
| Oxidative Damage to DNA and Repair | |||
| 8-OHdG ng/mL | 67.92±16.45 | 137.07±61.79 | 0.39 |
| hOGG1 ng/mL | 5.81±0.92 | 3.07±1.15 | 0.032** |
| Oxidants | |||
| LPO µM | 3.84 ± 0.21 | 3.90±0.22 | 0.34 |
| 8-Isoprostane pg/mL | 21.70±1.02 | 30.85±3.79 | 0.039** |
| Nitric oxide µM | 234.67±7.58 | 250.87±8.84 | 0.42 |
| Antioxidants | |||
| SOD U/mL | 0.36±0.03 | 0.42±0.07 | 0.75 |
| GPx nmol/min/mL | 2.06±0.23 | 2.09±0.18 | 0.23 |
| Total antioxidant capacity mM | 2.27±0.07 | 2.31±0.13 | 0.75 |
| Catalase mU/mL | 18.06±1.10 | 17.26±1.73 | 0.89 |
Notes: Values are mean ± SD, SEM or percentage. ***Chi-square test, *Student’s t-test, **Mann Whitney U-test.
Abbreviations: VAF, visceral abdominal fat; BMI, body mass index;T2DM, type 2 diabetes Mellitus; TNF, tumor necrosis factor alpha; IL-6, interleukin 6; 8-OHdG, 8-hydroxy-2ʹ-deoxyguanosine; hOGG1, human oxoguanin glycosylase; LPO, Lipoperoxides; SOD, Superoxide dismutase; GPx, Glutathione peroxidase.